Stereochemical Aspects of Nucleophilic Substitution Reactions of Haloalkanes and Haloarenes

IMPORTANT

Stereochemical Aspects of Nucleophilic Substitution Reactions of Haloalkanes and Haloarenes: Overview

This topic covers concepts, such as Basic Stereochemical Principles and Notations, Optically Active Compounds and Optical Activity, Dextrorotatory and Laevorotatory, Optical Isomers or Enantiomers and Optical Isomerism, Configuration, etc.

Important Questions on Stereochemical Aspects of Nucleophilic Substitution Reactions of Haloalkanes and Haloarenes

MEDIUM
IMPORTANT

Which of the following structures represents a chiral compound?

HARD
IMPORTANT

What kind of reagent would be needed to resolve a racemic amine, such as 2-aminobutane?

EASY
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A pure simple of 2-chlorobutane shows rotation of PPL by 30o in standard conditions. When above samples is made impure by mixing its opposite form, so that the composition of the mixture become 87.5 % d-form and 12.5 % l-form, then what will be the observed rotation for the mixture.

MEDIUM
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Consider the following compounds:

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Which one of the following is correct in respect of the above compounds?

MEDIUM
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Which of the following method is not used in the resolution of a racemic mixture?

HARD
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Which of the following compounds will give racemic mixture on nucleophilic substitution by OH- ion? Question Image

HARD
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 Compound A with molecular formula C6H12 has chirality but on hydrogenation compound A is converted into C6H14 compound B in which chirality disappear compound A is:

EASY
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How many chiral carbon atoms are present in 2, 3, 4- trichloropentane?

MEDIUM
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A solution of (−)−1-chloro-1-phenylethane in toluene racemises slowly in the presence of small amount of SbCl5, due to the formation of

MEDIUM
IMPORTANT

Molecules whose mirror image is non superimposable over them are known as chiral. Which of the following molecules is chiral in nature?